The antifibrotic adipose‐derived stromal cell: Grafted fat enriched with CD74+ adipose‐derived stromal cells reduces chronic radiation‐induced skin fibrosis

The antifibrotic adipose‐derived stromal cell: Grafted fat enriched with CD74+ adipose‐derived stromal cells reduces chronic radiation‐induced skin fibrosis

Abstract Fat grafting can reduce radiation‐induced fibrosis. Improved outcomes are found when fat grafts are enriched with adipose‐derived stromal cells (ASCs), implicating ASCs as key drivers of soft tissue regeneration. We have identified a subpopulation of ASCs positive for CD74 with enhanced ant...

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Bibliographic Details
Main Authors: Mimi R. Borrelli, Ronak A. Patel, Sandeep Adem, Nestor M. Diaz Deleon, Abra H. Shen, Jan Sokol, Sara Yen, Erin Y. Chang, Rahim Nazerali, Dung Nguyen, Arash Momeni, Kevin C. Wang, Michael T. Longaker, Derrick C. Wan
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Stem Cells Translational Medicine
Subjects:
adipose
adipose stem cells
FACS
stem cells
transplantation
Online Access:https://doi.org/10.1002/sctm.19-0317

Internet

https://doi.org/10.1002/sctm.19-0317

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