Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.

Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.

The humoral immune system responds to chronic hepatitis C virus (HCV) infection by producing neutralising antibodies (nAb). In this study we generated three HCV pseudoparticles in which E1E2 glycoprotein sequence was targeted by the host humoral immune system. We used patient derived virus free Fabs...

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Bibliographic Details
Main Authors: Amruta S Naik, Ania Owsianka, Brendan A Palmer, Ciaran J O'Halloran, Nicole Walsh, Orla Crosbie, Elizabeth Kenny-Walsh, Arvind H Patel, Liam J Fanning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0175349

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