PRL2 serves as a negative regulator in cell adaptation to oxidative stress

Abstract High levels of ROS cause oxidative stress, which plays a critical role in cell death. As a ROS effector protein, PRL2 senses ROS and controls phagocyte bactericidal activity during infection. Here we report PRL2 regulates oxidative stress induced cell death. PRL2 senses oxidative stress via...

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Bibliographic Details
Main Authors: Xinyue Du, Yang Zhang, Xiao Li, Qi Li, Chenyun Wu, Guangjie Chen, XiaoKui Guo, Yongqiang Weng, Zhaojun Wang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-019-0358-z

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