Self-Association of Okadaic Acid: Structural and Pharmacological Significance

Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this polyether for its targets together with its high specificity to inhibit certain protein phosphatases enables the differential study of these proteins. Crystallographic structu...

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Bibliographic Details
Main Authors: José J. Fernández, Antonio Hernández Daranas, Alberto Hernández Creus, Patricia G. Cruz, Manuel Norte
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/6/1866