Development of TaqMan-based quantitative PCR for sensitive and selective detection of toxigenic Clostridium difficile in human stools.

Clostridium difficile is the main cause of nosocomial diarrhea, but is also found in asymptomatic subjects that are potentially involved in transmission of C. difficile infection. A sensitive and accurate detection method of C. difficile, especially toxigenic strains is indispensable for the epidemi...

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Bibliographic Details
Main Authors: Hiroyuki Kubota, Takafumi Sakai, Agata Gawad, Hiroshi Makino, Takuya Akiyama, Eiji Ishikawa, Kenji Oishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4216139?pdf=render