A Model of an Autonomic Effector Control Loop

A Model of an Autonomic Effector Control Loop

A qualitative model of an autonomic effector control loop is presented, showing the components of information transmission. With reference to the pupil-light reflex and accommodation it is argued that injection of drugs such as pilocarpine forms an input to the forward loop of the system, whereas dr...

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Main Author: F M Toates
Format: Article
Language:English
Published: SAGE Publishing 1972-09-01
Series:Measurement + Control
Online Access:https://doi.org/10.1177/002029407200500902
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spelling doaj-7be305f1c6614aaba72ce01bc66ef02a2020-11-25T02:59:27ZengSAGE PublishingMeasurement + Control0020-29401972-09-01510.1177/002029407200500902A Model of an Autonomic Effector Control LoopF M Toates0 Laboratory of Experimental Psychology, University of Sussex, BrightonA qualitative model of an autonomic effector control loop is presented, showing the components of information transmission. With reference to the pupil-light reflex and accommodation it is argued that injection of drugs such as pilocarpine forms an input to the forward loop of the system, whereas drugs such as DFP and cycloplegics cause a change in gain. In these terms their effect on accomodative-convergence may be understood. Competition between certain miotic drugs as well as dose-response non-linearity is explained by reference to the model. It is proposed that under some conditions, properties of the open-loop system are responsible for denervation-sensitization.https://doi.org/10.1177/002029407200500902
collection DOAJ
language English
format Article
sources DOAJ
author F M Toates
spellingShingle F M Toates
A Model of an Autonomic Effector Control Loop
Measurement + Control
author_facet F M Toates
author_sort F M Toates
title A Model of an Autonomic Effector Control Loop
title_short A Model of an Autonomic Effector Control Loop
title_full A Model of an Autonomic Effector Control Loop
title_fullStr A Model of an Autonomic Effector Control Loop
title_full_unstemmed A Model of an Autonomic Effector Control Loop
title_sort model of an autonomic effector control loop
publisher SAGE Publishing
series Measurement + Control
issn 0020-2940
publishDate 1972-09-01
description A qualitative model of an autonomic effector control loop is presented, showing the components of information transmission. With reference to the pupil-light reflex and accommodation it is argued that injection of drugs such as pilocarpine forms an input to the forward loop of the system, whereas drugs such as DFP and cycloplegics cause a change in gain. In these terms their effect on accomodative-convergence may be understood. Competition between certain miotic drugs as well as dose-response non-linearity is explained by reference to the model. It is proposed that under some conditions, properties of the open-loop system are responsible for denervation-sensitization.
url https://doi.org/10.1177/002029407200500902
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