Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease

Abstract Introduction Mesenchymal stromal cells (MSCs) play an important role in the prevention of cell and tissue fibrosis. Senescence may decrease the function of MSCs during recovery from tissue and organ damage. Extracellular vesicles (EVs) released from MSCs contribute to the repair of kidney i...

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Bibliographic Details
Main Authors: Yan Wang, Yi Fang Guo, Guang Ping Fu, Chang Guan, Xin Zhang, Dong Gang Yang, Yun Cong Shi
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Old
Online Access:http://link.springer.com/article/10.1186/s13287-020-01792-7