A new design for a chronological release profile of etodolac from coated bilayer tablets: In-vitro and in-vivo assessment

Repeated dose medication usually maximizes adverse effects, while sustained release systems did not offer a fast onset of action. Etodolac was formulated to enable pulsatile and sustained drug release, which was chronologically more suitable as an anti-inflammatory drug. Eudragit® RSPO, Eudragit® RL...

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Bibliographic Details
Main Authors: Kirolos R. Georgy, Ragwa M. Farid, Randa Latif, Ehab R. Bendas
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123218300924