Detoxification of 1,2-dihydroxy- 4-allylbenzene, a major phenolic compound in Piper betle, through glucuronidation using S9 protein of rat liver (Sprague Dawley)
1,2-dihydroxy- 4-allylbenzene (DHAB) is a major compound in Piper betle leaf and also a metabolite of safrole metabolism. Epidemilogic studies showed people who have betel quid chewing habit are related to the incidence of oral submucous fibrosis and/or tumor formation. The aims of this research was...
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| Format: | Article |
| Language: | English |
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Universitas Ahmad Dahlan
2018-05-01
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| Series: | Pharmaciana |
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| Online Access: | http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/9194/pdf_64 |