Airway response to respiratory syncytial virus has incidental antibacterial effects

Respiratory syncytial virus (RSV) can trigger secondary airway bacterial infections. Here, by proteomics and metagenomics analyses of samples from Kenyan children, the authors report that RSV associates with Streptococcus burden and a local upper airway response with direct antibacterial properties.

Bibliographic Details
Main Authors: Charles J. Sande, James M. Njunge, Joyce Mwongeli Ngoi, Martin N. Mutunga, Timothy Chege, Elijah T. Gicheru, Elizabeth M. Gardiner, Agnes Gwela, Christopher A. Green, Simon B. Drysdale, James A. Berkley, D. James Nokes, Andrew J. Pollard
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10222-z
Description
Summary:Respiratory syncytial virus (RSV) can trigger secondary airway bacterial infections. Here, by proteomics and metagenomics analyses of samples from Kenyan children, the authors report that RSV associates with Streptococcus burden and a local upper airway response with direct antibacterial properties.
ISSN:2041-1723