A Tissue Engineered Model of Aging: Interdependence and Cooperative Effects in Failing Tissues

Abstract Aging remains a fundamental open problem in modern biology. Although there exist a number of theories on aging on the cellular scale, nearly nothing is known about how microscopic failures cascade to macroscopic failures of tissues, organs and ultimately the organism. The goal of this work...

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Bibliographic Details
Main Authors: A. Acun, D. C. Vural, P. Zorlutuna
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05098-2