The antagonism of 6-shogaol in high-glucose-activated NLRP3 inflammasome and consequent calcification of human artery smooth muscle cells
Abstract Background Vascular calcification is the major reason for high mortality of cardiovascular complications for diabetes. Interleukin (IL)-1β has been implicated in this pathogenesis, but its precise role and clinical evidence have not been clearly identified. Hence, this study was aimed to in...
Main Authors: | Te-Chuan Chen, Chia-Kung Yen, Ying-Chen Lu, Chung-Sheng Shi, Rong-Ze Hsieh, Shun-Fu Chang, Cheng-Nan Chen |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13578-019-0372-1 |
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