Proteasome inhibitors: situation and prospects (literature review and own data)

Multiple myeloma is a clonal B-cell malignancy characterized by proliferation of plasma cells that accumulate mainly in bone marrow and usually secrete monoclonal Ig and/or Ig light chains. The history of therapy development in this disease has more than 50 years. After ubiquitin-proteasome system o...

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Bibliographic Details
Main Authors: A. A. Rukavitsyn, O. A. Rukavitsyn
Format: Article
Language:Russian
Published: ABV-press 2016-10-01
Series:Onkogematologiâ
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/210