TGF-β1-containing exosomes derived from bone marrow mesenchymal stem cells promote proliferation, migration and fibrotic activity in rotator cuff tenocytes

TGF-β1-containing exosomes derived from bone marrow mesenchymal stem cells promote proliferation, migration and fibrotic activity in rotator cuff tenocytes

Objective: This study aimed to investigate effects of TGF-β1-containing exosomes derived from bone marrow mesenchymal stem cells (BMSC) on cell function of rotator cuff tenocytes and its implication to rotator cuff tear. Methods: The primary BMSC and rotator cuff tenocytes were extracted and culture...

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Bibliographic Details
Main Authors: Jia Li, Zheng-Peng Liu, Cong Xu, Ai Guo
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
BMSC
Exosomes
TGF-β1
Rotator cuff tear
Proliferation
Migration
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300547

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