Sequence polymorphism data of the hypervariable regions of mitochondrial DNA in the Yadav population of Haryana

• Main Authors: Kapil Verma, Sapna Sharma, Arun Sharma, Jyoti Dalal, Tapeshwar Bhardwaj
• Format: Article
• Language: English
• Published: Elsevier 2018-06-01
• Series: Data in Brief
• Online Access: http://www.sciencedirect.com/science/article/pii/S235234091830204X

Genetic variations among humans occur both within and among populations and range from single nucleotide changes to multiple-nucleotide variants. These multiple-nucleotide variants are useful for studying the relationships among individuals or various population groups. The study of human genetic variations can help scientists understand how different population groups are biologically related to one another. Sequence analysis of hypervariable regions of human mitochondrial DNA (mtDNA) has been successfully used for the genetic characterization of different population groups for forensic purposes. It is well established that different ethnic or population groups differ significantly in their mtDNA distributions. In the last decade, very little research has been conducted on mtDNA variations in the Indian population, although such data would be useful for elucidating the history of human population expansion across the world. Moreover, forensic studies on mtDNA variations in the Indian subcontinent are also scarce, particularly in the northern part of India. In this report, variations in the hypervariable regions of mtDNA were analyzed in the Yadav population of Haryana. Different molecular diversity indices were computed. Further, the obtained haplotypes were classified into different haplogroups and the phylogenetic relationship between different haplogroups was inferred. Keywords: Genetic variation, Hypervariable regions, mtDNA, Forensic, Yadav