Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Non-antibiotic selection systems could also serve as biocontainment strategies. Here the authors present a fluoride sensitivity selection system for use in yeast.

Bibliographic Details
Main Authors: Justin I. Yoo, Susanna Seppälä, Michelle A. OʼMalley
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19271-1
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spelling doaj-7b6a68b1c8f44c0d98be889e50d444242021-05-11T08:45:17ZengNature Publishing GroupNature Communications2041-17232020-10-011111910.1038/s41467-020-19271-1Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeastsJustin I. Yoo0Susanna Seppälä1Michelle A. OʼMalley2Department of Chemical Engineering, University of California Santa BarbaraDepartment of Chemical Engineering, University of California Santa BarbaraDepartment of Chemical Engineering, University of California Santa BarbaraNon-antibiotic selection systems could also serve as biocontainment strategies. Here the authors present a fluoride sensitivity selection system for use in yeast.https://doi.org/10.1038/s41467-020-19271-1
collection DOAJ
language English
format Article
sources DOAJ
author Justin I. Yoo
Susanna Seppälä
Michelle A. OʼMalley
spellingShingle Justin I. Yoo
Susanna Seppälä
Michelle A. OʼMalley
Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
Nature Communications
author_facet Justin I. Yoo
Susanna Seppälä
Michelle A. OʼMalley
author_sort Justin I. Yoo
title Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
title_short Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
title_full Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
title_fullStr Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
title_full_unstemmed Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
title_sort engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-10-01
description Non-antibiotic selection systems could also serve as biocontainment strategies. Here the authors present a fluoride sensitivity selection system for use in yeast.
url https://doi.org/10.1038/s41467-020-19271-1
work_keys_str_mv AT justiniyoo engineeredfluoridesensitivityenablesbiocontainmentandselectionofgeneticallymodifiedyeasts
AT susannaseppala engineeredfluoridesensitivityenablesbiocontainmentandselectionofgeneticallymodifiedyeasts
AT michelleaoʼmalley engineeredfluoridesensitivityenablesbiocontainmentandselectionofgeneticallymodifiedyeasts
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