Population structure of mixed Mycobacterium tuberculosis infection is strain genotype and culture medium dependent.

BACKGROUND: Molecular genotyping methods have shown infection with more than one Mycobacterium tuberculosis strain genotype in a single sputum culture, indicating mixed infection. AIM: This study aimed to develop a PCR-based genotyping tool to determine the population structure of M. tuberculosis st...

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Bibliographic Details
Main Authors: Madeleine Hanekom, Elizabeth M Streicher, Doreen Van de Berg, Helen Cox, Cheryl McDermid, Marlein Bosman, Nicolaas C Gey van Pittius, Tommie C Victor, Martin Kidd, Dick van Soolingen, Paul D van Helden, Robin M Warren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728311?pdf=render