Identification and Analysis of p53-Regulated Enhancers in Hepatic Carcinoma

Identification and Analysis of p53-Regulated Enhancers in Hepatic Carcinoma

Enhancers can act as cis-regulatory elements to control transcriptional regulation by recruiting transcription factors (TFs) in a distance and orientation-independent manner. However, it is still unclear how p53 participates in the enhancer network as TF in hepatic carcinoma under the condition of D...

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Bibliographic Details
Main Authors: Yin Zhang, Mingming Qian, Fei Tang, Qingqing Huang, Wenzhu Wang, Yanjing Li, Zhixue Li, Beiping Li, Zhengliang Qiu, Junjie Yue, Zhiyun Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
p53
enhancer
hepatic carcinoma
transcription factors
microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00668/full

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