Impact of C-rel inhibition of cord blood-derived B-, T-, and NK cells

Impact of C-rel inhibition of cord blood-derived B-, T-, and NK cells

The c-Rel transcription factor is a unique member of the nuclear factor (NF)-κB family that has a role in curtailing the proliferation, differentiation, cytokine production, and overall activity of B- and T-cells. In addition, c-Rel is a key regulator of apoptosis in that it influences the expressio...

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Bibliographic Details
Main Authors: Shirin Fallahi, Seyede Momeneh Mohammadi, Hamid Tayefi Nasrabadi, Alireza Alihemmati, Naser Samadi, Sanaz Gholami, Dariush Shanehbandi, Hojjatollah Nozad Charoudeh
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Immunotoxicology
Subjects:
c-Rel
CD34+ cells
cytokines
NF-κB
siRNA
cord blood
stem cell factor (SCF)
FLT3
Online Access:http://dx.doi.org/10.1080/1547691X.2016.1250849

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