QuilA-Adjuvanted T. gondii Lysate Antigens Trigger Robust Antibody and IFNγ+ T Cell Responses in Pigs Leading to Reduction in Parasite DNA in Tissues Upon Challenge Infection

QuilA-Adjuvanted T. gondii Lysate Antigens Trigger Robust Antibody and IFNγ+ T Cell Responses in Pigs Leading to Reduction in Parasite DNA in Tissues Upon Challenge Infection

Toxoplasma gondii is an intracellular parasite of all mammals and birds, responsible for toxoplasmosis. In healthy individuals T. gondii infections mostly remain asymptomatic, however this parasite causes severe morbidity and mortality in immunocompromised patients and congenital toxoplasmosis in pr...

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Bibliographic Details
Main Authors: Mizanur Rahman, Bert Devriendt, Ignacio Gisbert Algaba, Bavo Verhaegen, Pierre Dorny, Katelijne Dierick, Eric Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
pigs
TLA vaccine
QuilA
magnetic capture-qPCR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02223/full

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