A rapid molecular approach for chromosomal phasing.

A rapid molecular approach for chromosomal phasing.

Determining the chromosomal phase of pairs of sequence variants - the arrangement of specific alleles as haplotypes - is a routine challenge in molecular genetics. Here we describe Drop-Phase, a molecular method for quickly ascertaining the phase of pairs of DNA sequence variants (separated by 1-200...

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Bibliographic Details
Main Authors: John F Regan, Nolan Kamitaki, Tina Legler, Samantha Cooper, Niels Klitgord, George Karlin-Neumann, Catherine Wong, Shawn Hodges, Ryan Koehler, Svilen Tzonev, Steven A McCarroll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4349636?pdf=render

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