Co-administration of omega-3 fatty acids and metformin showed more desirable effects than the single therapy on indices of bone mineralisation but not gluco-regulatory and antioxidant markers in diabetic rats

Co-administration of omega-3 fatty acids and metformin showed more desirable effects than the single therapy on indices of bone mineralisation but not gluco-regulatory and antioxidant markers in diabetic rats

Although metformin (Met) is the most recommended anti-diabetogenic drug in type 2 diabetic state, the drug is known to compromise bone integrity. Like metformin, omega-3 fatty acids (ω-3) have gluco-regulatory action; however, it aids bone health. Therefore, the present study investigated the effect...

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Bibliographic Details
Main Authors: Wale Johnson Adeyemi, Luqman Aribidesi Olayaki, Tahir Ahmad Abdussalam, Tolulope Olaoluwa Fabiyi, Temidayo Luqman Raji, Adenike Amatur-Rahman Adetunji
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Omega-3 fatty acids
Metformin
Diabetes
Antioxidant
Glucose
Bone
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219352539

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