Preparation of psoralen polymer–lipid hybrid nanoparticles and their reversal of multidrug resistance in MCF-7/ADR cells

Preparation of psoralen polymer–lipid hybrid nanoparticles and their reversal of multidrug resistance in MCF-7/ADR cells

Multidrug resistance (MDR) is the leading cause of failure for breast cancer in the clinic. Thus far, polymer–lipid hybrid nanoparticles (PLN) loaded chemotherapeutic agents has been used to overcome MDR in breast cancer. In this study, we prepared psoralen polymer–lipid hybrid nanoparticles (PSO-PL...

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Bibliographic Details
Main Authors: Qingqing Huang, Tiange Cai, Qianwen Li, Yinghong Huang, Qian Liu, Bingyue Wang, Xi Xia, Qi Wang, John C. C. Whitney, Susan P. C. Cole, Yu Cai
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
breast cancer
pso-pln
optimal formulation
mcf-7/adr cells
multidrug resistance
Online Access:http://dx.doi.org/10.1080/10717544.2018.1464084

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