Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator

Objective. To evaluate the role of SIRT1 in small intestine damage following severe hemorrhagic shock and to investigate whether polydatin (PD) can activate SIRT1 in shock treatment. Research Design and Methods. The severe hemorrhagic shock model was reproduced in Sprague Dawley rats. Main Outcome M...

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Bibliographic Details
Main Authors: Zhenhua Zeng, Zhongqing Chen, Siqi Xu, Rui Song, Hong Yang, Ke-seng Zhao
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/965961