m5C RNA Methylation Primarily Affects the ErbB and PI3K–Akt Signaling Pathways in Gastrointestinal Cancer

m5C RNA Methylation Primarily Affects the ErbB and PI3K–Akt Signaling Pathways in Gastrointestinal Cancer

5-Methylcytosine (m5C) is a kind of methylation modification that occurs in both DNA and RNA and is present in the highly abundant tRNA and rRNA. It has an important impact on various human diseases including cancer. The function of m5C is modulated by regulatory proteins, including methyltransferas...

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Bibliographic Details
Main Authors: Shixin Xiang, Yongshun Ma, Jing Shen, Yueshui Zhao, Xu Wu, Mingxing Li, Xiao Yang, Parham Jabbarzadeh Kaboli, Fukuan Du, Huijiao Ji, Yuan Zheng, Xiang Li, Jing Li, Qinglian Wen, Zhangang Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
m5C
RNA methylation
ErbB
PI3K–Akt
gastrointestinal cancer
survival
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.599340/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2020.599340/full

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