Novel calpain families and novel mechanisms for calpain regulation in Aplysia.

Calpains are a family of intracellular proteases defined by a conserved protease domain. In the marine mollusk Aplysia californica, calpains are important for the induction of long-term synaptic plasticity and memory, at least in part by cleaving protein kinase Cs (PKCs) into constitutively active k...

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Bibliographic Details
Main Authors: Margaret H Hastings, Katrina Gong, Alexander Freibauer, Caitlin Courchesne, Xiaotang Fan, Wayne S Sossin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5650170?pdf=render