Lipoarabinomannan in sputum to detect bacterial load and treatment response in patients with pulmonary tuberculosis: Analytic validation and evaluation in two cohorts.

Lipoarabinomannan in sputum to detect bacterial load and treatment response in patients with pulmonary tuberculosis: Analytic validation and evaluation in two cohorts.

<h4>Background</h4>Lipoarabinomannan (LAM) is a major antigen of Mycobacterium tuberculosis (MTB). In this report, we evaluated the ability of a novel immunoassay to measure concentrations of LAM in sputum as a biomarker of bacterial load prior to and during treatment in pulmonary tuberc...

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Main Authors: Masanori Kawasaki, Carmenchu Echiverri, Lawrence Raymond, Elizabeth Cadena, Evelyn Reside, Maria Tarcela Gler, Tetsuya Oda, Ryuta Ito, Ryo Higashiyama, Kiyonori Katsuragi, Yongge Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002780

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