Neisseria Heparin Binding Antigen is targeted by the human alternative pathway C3-convertase.

Neisseria Heparin Binding Antigen is targeted by the human alternative pathway C3-convertase.

Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein specific for Neisseria and constitutes one of the three main protein antigens of the Bexsero vaccine. Meningococcal and human proteases, cleave NHBA protein upstream or downstream of a conserved Arg-rich region, respectively....

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Bibliographic Details
Main Authors: Martina Di Fede, Massimiliano Biagini, Elena Cartocci, Carlo Parillo, Alessandra Greco, Manuele Martinelli, Sara Marchi, Alfredo Pezzicoli, Isabel Delany, Silvia Rossi Paccani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5868813?pdf=render

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http://europepmc.org/articles/PMC5868813?pdf=render

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