Mesotherapy using Vitamin C as an anti-inflammatory agent in persistent gingival inflammation: A case series

• Main Authors: Bhavya Brahmavar, Safiya Fatima Khan, Asim Mustafa Khan
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Journal of Indian Society of Periodontology
• Subjects: anti-inflammatory agents; inflammation; mesotherapy; periodontal therapy; vitamin c
• Online Access: http://www.jisponline.com/article.asp?issn=0972-124X;year=2021;volume=25;issue=3;spage=203;epage=206;aulast=Brahmavar

Background: Mesotherapy is a minimally invasive procedure which involves local intradermal therapy (LIT) with biologically active substances given in minor quantities to the area of pathology. Vitamin C is an important antioxidant agent which can modulate the attenuation of inflammatory process and enhance tissue repair. Aim: The aim of this study was to investigate the efficacy of local injections of Vitamin C for treating persisting inflammation of the gingiva. Materials and Methods: After phase I therapy was completed, five patients with persisting chronic inflammation of the gingiva were injected with the same dosages of Vitamin C into the gingival tissues. Patients were evaluated each week for resolution of gingival inflammation. Results: Clinical observation showed a significant improvement in inflammation of the injected sites during recall appointments. Conclusions: LIT with Vitamin C has a synergistic interaction along with scaling and root planing in the treatment of persistent gingival inflammation.