Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department?
Objectives: Scoring systems have been used to risk stratify in intensive care units (ICU), but not routinely used in emergency departments. The aim of this study was to determine accuracy for predicting mortality in emergency medicine with Sequential Organ Failure Assessment (SOFA), Mortality in ED...
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doaj-7af5e29f90ea42a2a9d9bffef950db542021-02-02T05:14:40ZengWolters Kluwer Medknow PublicationsTurkish Journal of Emergency Medicine2452-24732017-03-011712528Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department?Merve Gunes Ozaydin0Ozlem Guneysel1Fatma Saridogan2Vehbi Ozaydin3Dr Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey; Corresponding author. Semsi Denizer Cevizli Mevki Kartal, Istanbul, Turkey.Dr Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, TurkeyDr Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, TurkeyIstanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, TurkeyObjectives: Scoring systems have been used to risk stratify in intensive care units (ICU), but not routinely used in emergency departments. The aim of this study was to determine accuracy for predicting mortality in emergency medicine with Sequential Organ Failure Assessment (SOFA), Mortality in ED Sepsis (MEDS) score and Simplified Acute Physiology Score (SAPSII). Methods: This is a prospective observational study. Patients presenting with evidence of sepsis were all included. SAPSII, MEDS, and SOFA scores were calculated. Analysis compared areas under the receiver operator characteristic (ROC) curves for 28-day mortality. Results: Two hundred patients were included; consisting of 31 (14.3%) septic shock. 138 (69%) severe sepsis and 31 (15.5%) infection without organ dysfunction. 53 (26.5%) patients died within 28 days.Area under the ROC curve for mortality was 0.76 for MEDS (0.69–0.82), 0.70 for SAPSII (0.62–0.78); and 1.68 for SOFA (0.60–0.76) scores. Pair wise comparison of AUC between MEDS, SAPSII, SOFA and Lactate were not significant. Conclusion: According to our results; SOFA, SAPSII and MEDS were not sufficient to predict mortality. Also this result, MEDS was better than other scoring system. Keywords: Sepsis, Septic shock, Scoring systems, SOFA, SAPSII, MEDS, Lactate, Emergency medicinehttp://www.sciencedirect.com/science/article/pii/S2452247316301042 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Merve Gunes Ozaydin Ozlem Guneysel Fatma Saridogan Vehbi Ozaydin |
spellingShingle |
Merve Gunes Ozaydin Ozlem Guneysel Fatma Saridogan Vehbi Ozaydin Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? Turkish Journal of Emergency Medicine |
author_facet |
Merve Gunes Ozaydin Ozlem Guneysel Fatma Saridogan Vehbi Ozaydin |
author_sort |
Merve Gunes Ozaydin |
title |
Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
title_short |
Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
title_full |
Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
title_fullStr |
Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
title_full_unstemmed |
Are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
title_sort |
are scoring systems sufficient for predicting mortality due to sepsis in the emergency department? |
publisher |
Wolters Kluwer Medknow Publications |
series |
Turkish Journal of Emergency Medicine |
issn |
2452-2473 |
publishDate |
2017-03-01 |
description |
Objectives: Scoring systems have been used to risk stratify in intensive care units (ICU), but not routinely used in emergency departments. The aim of this study was to determine accuracy for predicting mortality in emergency medicine with Sequential Organ Failure Assessment (SOFA), Mortality in ED Sepsis (MEDS) score and Simplified Acute Physiology Score (SAPSII). Methods: This is a prospective observational study. Patients presenting with evidence of sepsis were all included. SAPSII, MEDS, and SOFA scores were calculated. Analysis compared areas under the receiver operator characteristic (ROC) curves for 28-day mortality. Results: Two hundred patients were included; consisting of 31 (14.3%) septic shock. 138 (69%) severe sepsis and 31 (15.5%) infection without organ dysfunction. 53 (26.5%) patients died within 28 days.Area under the ROC curve for mortality was 0.76 for MEDS (0.69–0.82), 0.70 for SAPSII (0.62–0.78); and 1.68 for SOFA (0.60–0.76) scores. Pair wise comparison of AUC between MEDS, SAPSII, SOFA and Lactate were not significant. Conclusion: According to our results; SOFA, SAPSII and MEDS were not sufficient to predict mortality. Also this result, MEDS was better than other scoring system. Keywords: Sepsis, Septic shock, Scoring systems, SOFA, SAPSII, MEDS, Lactate, Emergency medicine |
url |
http://www.sciencedirect.com/science/article/pii/S2452247316301042 |
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