α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

<p><b>Abstract</b></p> <p><b>Background</b></p> <p>Although evidence suggests that the prevalence of Parkinson’s disease (PD) is lower in smokers than in non-smokers, the mechanisms of nicotine-induced neuroprotection remain unclear. Stimulation...

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Bibliographic Details
Main Authors: Liu Yuan, Hu Jun, Wu Jie, Zhu Chenlei, Hui Yujian, Han Yaping, Huang Zuhu, Ellsworth Kevin, Fan Weimin
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
α7 nicotinic acetylcholine receptor
Parkinson’s disease
Astrocyte
Neuroinflammation
Neuroprotection
Online Access:http://www.jneuroinflammation.com/content/9/1/98

Internet

http://www.jneuroinflammation.com/content/9/1/98

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