The tumor therapy landscape of synthetic lethality
Various methods have been proposed to identify synthetic lethality interactions, but selective treatment opportunities for various tumors have not yet been explored. Here, the authors develop the Synthetic Lethality Knowledge Graph webserver (SLKG, http://www.slkg.net) to explore the comprehensive t...
Main Authors: | Biyu Zhang, Chen Tang, Yanli Yao, Xiaohan Chen, Chi Zhou, Zhiting Wei, Feiyang Xing, Lan Chen, Xiang Cai, Zhiyuan Zhang, Shuyang Sun, Qi Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-21544-2 |
Similar Items
-
The Landscape of Tumor Fusion Neoantigens: A Pan-Cancer Analysis
by: Zhiting Wei, et al.
Published: (2019-11-01) -
Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation
by: Win Topatana, et al.
Published: (2020-09-01) -
Synthetic Lethal Screening for YJR129c Gene of Saccharomyces cerevisiae
by: Kuo-Chen Chen, et al.
Published: (2009) -
Syn-Lethality: An Integrative Knowledge Base of Synthetic Lethality towards Discovery of Selective Anticancer Therapies
by: Xue-juan Li, et al.
Published: (2014-01-01) -
Protocol for Comprehensive Synthetic Lethality Screens
by: Damia Romero-Moya, et al.
Published: (2020-06-01)