Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

Summary: The heat shock protein 90 (Hsp90) chaperone functions as a protein-folding buffer and plays a role promoting the evolution of new heritable traits. To better understand how Hsp90 can affect mRNA translation, we screen more than 1,600 factors involved in mRNA regulation for physical interact...

Full description

Bibliographic Details
Main Authors: Peter Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune, Erinc Hallacli, Greg A. Newby, Can Kayatekin, David Pincus, Susan Lindquist
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
prions
epigentic regualtion
cellular memory
mRNA translation
Hsp90
yeast
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720309864

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720309864

Similar Items