| Summary: | We analyzed the incidence and the clinical and laboratory characteristics of <i>Staphylococcus lugdunensis</i> urinary tract infections (UTIs) during a 10-year period (2009−2018) and compared them with those of <i>Staphylococcus saprophyticus</i> UTIs. A total of 38 and 162 episodes of <i>S. lugdunensis</i> and <i>S. saprophyticus</i> UTIs were observed. The number of <i>S. saprophyticus</i> UTIs was stable throughout the 10 years, whereas there was an obvious surge in the apparent number of <i>S. lugdunensis</i> UTIs since 2014, coinciding with the commencement of a routine use of MALDI-TOF MS. Univariate analysis showed that male sex (<i>p</i> < 0.001), advanced age (<i>p</i> < 0.001), hospital-acquired infections, (<i>p</i> < 0.001), upper UTI (<i>p</i> < 0.005), polymicrobial infections (<i>p</i> < 0.05), hypertension (<i>p</i> < 0.001), solid-organ malignancies (<i>p</i> < 0.001), renal stones (<i>p</i> < 0.001), urinary stricture (<i>p</i> < 0.05), vesicoureteral reflux (<i>p</i> < 0.001), and presence of a urinary catheter (<i>p</i> < 0.001) were significantly associated with <i>S. lugdunensis</i> UTI. Multivariable analysis revealed that <i>S. lugdunensis</i> UTI was associated with male sex (OR = 6.08, <i>p</i> < 0.05), solid-organ malignancies (OR = 12.27, <i>p</i> < 0.01), and urological system abnormalities (OR = 7.44, <i>p</i> < 0.05). There were significant differences in the patient population affected and predisposing factors between <i>S. lugdunensis</i> and <i>S. saprophyticus</i> UTIs.
|
|---|
