Fontan-associated liver disease and hepatocellular carcinoma in adults

Abstract The Fontan operation creates a unique circulation, and is a palliative therapy for patients with single-ventricle congenital heart disease. Increased venous pressure and decreased cardiac output and hepatic venous drainage result in sinusoidal dilatation around the central veins. This cause...

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Bibliographic Details
Main Authors: Tomomi Kogiso, Katsutoshi Tokushige
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78840-y

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