Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes

<p>Abstract</p> <p>Background</p> <p>Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and has the potential to discl...

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Bibliographic Details
Main Authors: Cantarella Daniela, Fu Limin, Mira Alessia, Isella Claudio, Martelli Maria, Medico Enzo
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/254