Differential modulation of Ahr and Arid5a: A promising therapeutic strategy for autoimmune encephalomyelitis

Differential modulation of Ahr and Arid5a: A promising therapeutic strategy for autoimmune encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease that involves demyelination of axons in the central nervous system (CNS) and affects patients worldwide. It has been demonstrated that ligand-activated aryl hydrocarbon receptor (Ahr) ameliorates experimental autoimmune encephalomyelitis (EAE), a muri...

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Bibliographic Details
Main Authors: Abdullah Alzahrani, Hamza Hanieh
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Saudi Pharmaceutical Journal
Subjects:
Ahr
Arid5a
Inflammation
Autoimmunity
Multiple sclerosis
Therapeutic
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420302425

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