Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.

Background: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ability, functional equivalence appears to be at lea...

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Main Authors: Kristine eOostra, Anke eVan Bladel, Ann Christiane Leen Vanhoonacker, Guy eVingerhoets
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00005/full
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spelling doaj-7a9e172856d04c3c8719501831cb8eb52020-11-25T00:55:24ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532016-02-011010.3389/fnbeh.2016.00005174691Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.Kristine eOostra0Anke eVan Bladel1Ann Christiane Leen Vanhoonacker2Guy eVingerhoets3University hospital GhentGhent UniversityUniversity hospital GhentGhent UniversityBackground: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ability, functional equivalence appears to be at least partially preserved in stroke patients.Aim: to identify brain regions that are mandatory for preserved motor imagery ability after stroke.Method: thirty-seven patients with hemiplegia after a first time stroke participated. Motor imagery ability was measured using a Motor Imagery questionnaire and temporal congruence test. A voxelwise lesion symptom mapping approach was used to identify neural correlates of motor imagery in this cohort within the first year post-stroke.Results: poor motor imagery vividness was associated with lesions in the left putamen, left ventral premotor cortex and long association fibres linking parieto-occipital regions with the dorsolateral premotor and prefrontal areas. Poor temporal congruence was otherwise linked to lesions in the more rostrally located white matter of the superior corona radiata. Conclusion: This voxel-based lesion symptom mapping study confirms the association between white matter tract lesions and impaired motor imagery ability, thus emphasizing the importance of an intact fronto-parietal network for motor imagery. Our results further highlight the crucial role of the basal ganglia and premotor cortex when performing motor imagery tasks.http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00005/fullBasal GangliaStrokewhite matterMotor Imagerylesion symptom mapping
collection DOAJ
language English
format Article
sources DOAJ
author Kristine eOostra
Anke eVan Bladel
Ann Christiane Leen Vanhoonacker
Guy eVingerhoets
spellingShingle Kristine eOostra
Anke eVan Bladel
Ann Christiane Leen Vanhoonacker
Guy eVingerhoets
Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
Frontiers in Behavioral Neuroscience
Basal Ganglia
Stroke
white matter
Motor Imagery
lesion symptom mapping
author_facet Kristine eOostra
Anke eVan Bladel
Ann Christiane Leen Vanhoonacker
Guy eVingerhoets
author_sort Kristine eOostra
title Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
title_short Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
title_full Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
title_fullStr Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
title_full_unstemmed Damage to fronto-parietal networks impairs motor imagery ability after stroke:A voxel-based lesion symptom mapping study.
title_sort damage to fronto-parietal networks impairs motor imagery ability after stroke:a voxel-based lesion symptom mapping study.
publisher Frontiers Media S.A.
series Frontiers in Behavioral Neuroscience
issn 1662-5153
publishDate 2016-02-01
description Background: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ability, functional equivalence appears to be at least partially preserved in stroke patients.Aim: to identify brain regions that are mandatory for preserved motor imagery ability after stroke.Method: thirty-seven patients with hemiplegia after a first time stroke participated. Motor imagery ability was measured using a Motor Imagery questionnaire and temporal congruence test. A voxelwise lesion symptom mapping approach was used to identify neural correlates of motor imagery in this cohort within the first year post-stroke.Results: poor motor imagery vividness was associated with lesions in the left putamen, left ventral premotor cortex and long association fibres linking parieto-occipital regions with the dorsolateral premotor and prefrontal areas. Poor temporal congruence was otherwise linked to lesions in the more rostrally located white matter of the superior corona radiata. Conclusion: This voxel-based lesion symptom mapping study confirms the association between white matter tract lesions and impaired motor imagery ability, thus emphasizing the importance of an intact fronto-parietal network for motor imagery. Our results further highlight the crucial role of the basal ganglia and premotor cortex when performing motor imagery tasks.
topic Basal Ganglia
Stroke
white matter
Motor Imagery
lesion symptom mapping
url http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00005/full
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