Transitional states in child neurology (neurocontinuum)

• Main Author: B. A. Kobrinskii
• Format: Article
• Language: Russian
• Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2019-11-01
• Series: Rossijskij Vestnik Perinatologii i Pediatrii
• Subjects: children; continuum of pathological processes; children’s psychoneurology; transitional states; quasicontinuum of dynamic changes; mathematical models; hereditary defects; mitochondrial disorders
• Online Access: https://www.ped-perinatology.ru/jour/article/view/963
• ISSN: 1027-4065; 2500-2228

The article is devoted to the issue of transitional states in child psychoneurology, based on the general concept of a continuum of transitional states from normal variants to severe chronic diseases. The article discusses borderline psychoneurology disorders associated with mitochondrial dysfunction and various genetic defects. A significant passage is devoted to convulsive states and epilepsy. The autism spectrum analyzed both as a aggregate of nosologies and in combination with epilepsy. The author proposes the concept of quasicontinuum of cognitive development in the spectrum of child autism. There are presented the transitions of various forms of hysteria. Also the authors provide the data on the similar etiology of impaired coordination and cerebral palsy, which can be considered as a single continual process. As possible methods of dividing the continuum into separate forms there are works on the so-called signal features and a dynamics model for estimating time limits of transition states, also the operators to determine the value of factors characterizing transition states, are presented.