Lower Salinomycin Concentration Increases Apoptotic Detachment in High-Density Cancer Cells

Lower Salinomycin Concentration Increases Apoptotic Detachment in High-Density Cancer Cells

The present study identified a novel salinomycin (Sal) sensitization mechanism in cancer. We tested whether Sal reduced proliferation in a high-density population by counting attached cell numbers after Sal treatment. Sal reduced proliferation in high-density cell populations. Longer exposure to Sal...

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Bibliographic Details
Main Authors: Sungpil Yoon, Hyung Sik Kim, Ju-Hwa Kim, Tae Young Kim, Suntaek Hong
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:International Journal of Molecular Sciences
Subjects:
salinomycin
apoptosis
high cell density
spaces among cells
cellular detachment
lower concentration
Online Access:http://www.mdpi.com/1422-0067/13/10/13169

Internet

http://www.mdpi.com/1422-0067/13/10/13169

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