The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development

The basic helix–loop–helix/Per-ARNT-SIM (bHLH-PAS) proteins are a family of transcription factors regulating expression of a wide range of genes involved in different functions, ranging from differentiation and development control by oxygen and toxins sensing to circadian clock setting. In addition...

Full description

Bibliographic Details
Main Authors: Marta Kolonko-Adamska, Vladimir N. Uversky, Beata Greb-Markiewicz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
disease-associated mutation
intrinsically disordered region (IDR)
liquid-liquid phase separation (LLPS)
post-translational modifications (PTM)
Ahr
AhR
Online Access:https://www.mdpi.com/1422-0067/22/6/2868

Similar Items

Similar Items