The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development

The basic helix–loop–helix/Per-ARNT-SIM (bHLH-PAS) proteins are a family of transcription factors regulating expression of a wide range of genes involved in different functions, ranging from differentiation and development control by oxygen and toxins sensing to circadian clock setting. In addition...

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Bibliographic Details
Main Authors: Marta Kolonko-Adamska, Vladimir N. Uversky, Beata Greb-Markiewicz
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
disease-associated mutation
intrinsically disordered region (IDR)
liquid-liquid phase separation (LLPS)
post-translational modifications (PTM)
Ahr
AhR
Online Access:https://www.mdpi.com/1422-0067/22/6/2868

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https://www.mdpi.com/1422-0067/22/6/2868

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