The stability of carbapenems before and after admixture to PMMA-cement used for replacement surgery caused by Gram-negative bacteria

The stability of carbapenems before and after admixture to PMMA-cement used for replacement surgery caused by Gram-negative bacteria

Abstract Background Prosthetic joint infection (PJI) is a serious complication of orthopedic implant surgery. Treatment often includes the use of an antibiotic-loaded Polymethyl methacrylate (PMMA) bone cement spacer. Several antibiotics are commonly used for the preparation of these spacers, but du...

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Bibliographic Details
Main Authors: Matthias Schmid, Oliver Steiner, Lisa Fasshold, Walter Goessler, Anna-Maria Holl, Klaus-Dieter Kühn
Format: Article
Language:English
Published: BMC 2020-08-01
Series:European Journal of Medical Research
Subjects:
Imipenem
Meropenem
Carbapenems
PMMA cement
Periprosthetic joint infection
Local antibiotic therapy
Online Access:http://link.springer.com/article/10.1186/s40001-020-00428-z

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http://link.springer.com/article/10.1186/s40001-020-00428-z

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