The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line

Abstract Microglia, resident macrophages of the brain that act as primary immune cells, play essential roles in innate immunity and neuroinflammatory pathologies. Microglial cells are rapidly activated in response to infection and inflammation/injury, associated with the expression of proinflammator...

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Bibliographic Details
Main Authors: Mina Baek, Eunyoung Yoo, Hae In Choi, Ga Yeong An, Jin Choul Chai, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87828-1