Modification of histone acetylation facilitates hepatic differentiation of human bone marrow mesenchymal stem cells.

Modification of histone acetylation facilitates hepatic differentiation of human bone marrow mesenchymal stem cells.

The multi-potentiality of mesenchymal stem cells makes them excellent options for future tissue engineering and clinical therapy, including liver injury. In this study, we investigated the effects of valproic acid (VPA), a direct inhibitor of histone deacetylase (HDAC), on the hepatic differentiatio...

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Bibliographic Details
Main Authors: Xuejun Dong, Ruolang Pan, Hui Zhang, Chao Yang, Jianzhong Shao, Lixin Xiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3642107?pdf=render

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