A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility

A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility

Background: The composition of the bile acid (BA) pool is closely associated with obesity and is modified by gut microbiota. Perturbations of gut microbiota shape the BA composition, which, in turn, may alter important BA signaling and affect host metabolism. Methods: We investigated BA composition...

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Bibliographic Details
Main Authors: Meilin Wei, Fengjie Huang, Ling Zhao, Yunjing Zhang, Wei Yang, Shouli Wang, Mengci Li, Xiaolong Han, Kun Ge, Chun Qu, Cynthia Rajani, Guoxiang Xie, Xiaojiao Zheng, Aihua Zhao, Zhaoxiang Bian, Wei Jia
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:EBioMedicine
Subjects:
Obesity
Bile acids
Gut microbiota
Energy expenditure
GLP-1
UCP1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420301419

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http://www.sciencedirect.com/science/article/pii/S2352396420301419

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