Evaluating target silencing by short hairpin RNA mediated by the group I intron in cultured mammalian cells

<p>Abstract</p> <p>Background</p> <p>The group I intron, a ribozyme that catalyzes its own splicing reactions in the absence of proteins <it>in vitro</it>, is a potential target for rational engineering and attracted our interest due to its potential utility...

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Bibliographic Details
Main Authors: Takaku Hiroshi, Ishitu Yoshio, Noguchi Kousei
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/79