Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

Abstract Background Vaccines are the most reliable alternative to elicit sterile immunity against malaria but their development has been hindered by polymorphisms and strain-specificity in previously studied antigens. New vaccine candidates are therefore urgently needed. Highly conserved Plasmodium...

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Bibliographic Details
Main Authors: Olusola Ajibaye, Akinniyi A. Osuntoki, Emmanuel O. Balogun, Yetunde A. Olukosi, Bamidele A. Iwalokun, Kolapo M. Oyebola, Kenji Hikosaka, Yoh-ichi Watanabe, Godwin U. Ebiloma, Kiyoshi Kita, Alfred Amambua-Ngwa
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Malaria Journal
Subjects:
Polymorphisms
Reticulocyte-binding protein homologue-5
Haplotypes
Histocompatibility
Gene flow
Linkage
Online Access:https://doi.org/10.1186/s12936-019-3096-0

Internet

https://doi.org/10.1186/s12936-019-3096-0

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