BoHV-4-based vector delivering Ebola virus surface glycoprotein

BoHV-4-based vector delivering Ebola virus surface glycoprotein

Abstract Background Ebola virus (EBOV) is a Category A pathogen that is a member of Filoviridae family that causes hemorrhagic fever in humans and non-human primates. Unpredictable and devastating outbreaks of disease have recently occurred in Africa and current immunoprophylaxis and therapies are l...

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Bibliographic Details
Main Authors: Alfonso Rosamilia, Sarah Jacca, Giulia Tebaldi, Silvia Tiberti, Valentina Franceschi, Francesca Macchi, Sandro Cavirani, Gary Kobinger, Donald P. Knowles, Gaetano Donofrio
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Translational Medicine
Subjects:
Ebola virus
Bovine herpesvirus 4
Vaccine platform
Viral vector
Recombineering
Online Access:http://link.springer.com/article/10.1186/s12967-016-1084-5

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