Facile biosynthesis of Ag-NPs using Otostegia limbata plant extract: Physical characterization and auspicious biological activities

Silver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron...

Full description

Bibliographic Details
Main Authors: Rizwan Kausar, Muhammad Ashraf Shaheen, Qaisar Maqbool, Sania Naz, Mudassar Nazar, Fazal Abbas, Talib Hussain, Umer Younas, Muhammad Fahad Shams
Format: Article
Language:English
Published: AIP Publishing LLC 2016-09-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4962660
Description
Summary:Silver nanoparticles (Ag-NPs) synthesized through reduction by Otostegia limbata green extract are, hereby, reported for the first time. It is very interesting to observe that in this case, O. limbata plant extract acts as a strong chelating agent in Ag-NPs formation through AgNO3. Scanning electron microscope (SEM) studies expose that Ag-NPs formation is highly homogenous and spherical with mean particle size of 32±0.8 nm. A typical Ag absorption peak has been observed at 419 nm by ultra violet (UV)-visible spectroscopy which have endorsed the successful formation of single phase Ag-NPs. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) examination further validates the crystalline pure phase structure of Ag-NPs. Promising results have been recorded against protein kinase inhibition assay and antibacterial assay having prominent pathogenic strains. Our present study explores that biosynthesized eco-friendly Ag-NPs have great potential, in the future, for anticancer drug development with wide range pharmaceutical applications.
ISSN:2158-3226